BDBM82258 CAS_114798-26-4::Losartan::NSC_3961

SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Data  20 KI  54 IC50  8 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 82258   

LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataKi:  32nMAssay Description:Tested for in vitro binding affinity against angiotensin II receptor of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  19nMAssay Description:Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  13nMAssay Description:Competitive inhibition of Angiotensin II receptor binding of radiolabeled AII to rat adrenal glomerulosa tissue by 50%More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  36nMAssay Description:Tested in vitro for inhibition of [125I]AII to rat uterine membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed